<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2025 Workiva-->
<!--r:6b339be5-6435-47bb-b3b6-63b1e20f8555,g:56c7191c-40e5-4afd-a283-8d34dcc29625-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.bioscrip.com/role/CONDENSEDCONSOLIDATEDBALANCESHEETS" xlink:type="simple" xlink:href="bios-20250630.xsd#CONDENSEDCONSOLIDATEDBALANCESHEETS"/>
  <link:calculationLink xlink:role="http://www.bioscrip.com/role/CONDENSEDCONSOLIDATEDBALANCESHEETS" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_d4a49a51-60c7-4d93-917f-6d228fe24ba3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalCommonStock_815c968c-1458-47cb-98cc-bb3a2a594ff3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AdditionalPaidInCapitalCommonStock"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_d4a49a51-60c7-4d93-917f-6d228fe24ba3" xlink:to="loc_us-gaap_AdditionalPaidInCapitalCommonStock_815c968c-1458-47cb-98cc-bb3a2a594ff3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockValue_938a97c4-6335-4336-93b3-9a53f212f58c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PreferredStockValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_d4a49a51-60c7-4d93-917f-6d228fe24ba3" xlink:to="loc_us-gaap_PreferredStockValue_938a97c4-6335-4336-93b3-9a53f212f58c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockCommonValue_095bc2e1-0a81-4bc9-810d-8d400fe3002a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_TreasuryStockCommonValue"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_d4a49a51-60c7-4d93-917f-6d228fe24ba3" xlink:to="loc_us-gaap_TreasuryStockCommonValue_095bc2e1-0a81-4bc9-810d-8d400fe3002a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_991f78a7-fbd0-4dec-b7cf-86f0cd3ff856" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_d4a49a51-60c7-4d93-917f-6d228fe24ba3" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_991f78a7-fbd0-4dec-b7cf-86f0cd3ff856" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_fce39db1-c819-46e9-9530-57f327d4be35" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockValue"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_d4a49a51-60c7-4d93-917f-6d228fe24ba3" xlink:to="loc_us-gaap_CommonStockValue_fce39db1-c819-46e9-9530-57f327d4be35" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_0c987e86-1711-4490-b81e-d124bde1b182" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_d4a49a51-60c7-4d93-917f-6d228fe24ba3" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_0c987e86-1711-4490-b81e-d124bde1b182" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_7457ed91-3160-4962-98a6-0ab6e7ec7e8d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_e4f61751-b748-4073-9345-d8bad75e19de" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_7457ed91-3160-4962-98a6-0ab6e7ec7e8d" xlink:to="loc_us-gaap_StockholdersEquity_e4f61751-b748-4073-9345-d8bad75e19de" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_aa1ca4a8-87e8-4704-8474-76e2cac66467" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Liabilities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_7457ed91-3160-4962-98a6-0ab6e7ec7e8d" xlink:to="loc_us-gaap_Liabilities_aa1ca4a8-87e8-4704-8474-76e2cac66467" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_8c8f7166-a644-426e-b71a-d92ab057d237" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_5e1f815a-c543-4509-afcf-07bd9523f300" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_8c8f7166-a644-426e-b71a-d92ab057d237" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_5e1f815a-c543-4509-afcf-07bd9523f300" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_590c346d-b6b4-4fc6-805d-a5b1bde7c26e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_8c8f7166-a644-426e-b71a-d92ab057d237" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_590c346d-b6b4-4fc6-805d-a5b1bde7c26e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_b379dbe5-1c62-4b55-9836-0c7bcf9c1709" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryNet"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_8c8f7166-a644-426e-b71a-d92ab057d237" xlink:to="loc_us-gaap_InventoryNet_b379dbe5-1c62-4b55-9836-0c7bcf9c1709" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_ff4b533f-a416-4225-a988-e7843d1831e2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_8c8f7166-a644-426e-b71a-d92ab057d237" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_ff4b533f-a416-4225-a988-e7843d1831e2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_491592fc-3c72-4cb7-a0cb-92f2b3da63e0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_817db3b9-15f8-4855-b4f2-6d75600ad291" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_491592fc-3c72-4cb7-a0cb-92f2b3da63e0" xlink:to="loc_us-gaap_AssetsCurrent_817db3b9-15f8-4855-b4f2-6d75600ad291" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsNoncurrent_b819f1ec-95cc-4b24-a890-8003f0b70aba" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_491592fc-3c72-4cb7-a0cb-92f2b3da63e0" xlink:to="loc_us-gaap_AssetsNoncurrent_b819f1ec-95cc-4b24-a890-8003f0b70aba" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsNoncurrent_0947e487-3474-40a1-b8da-bfba6c9733a0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsNoncurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_9751f9ca-f415-4d46-970a-24da1effb283" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsNoncurrent_0947e487-3474-40a1-b8da-bfba6c9733a0" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_9751f9ca-f415-4d46-970a-24da1effb283" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_bios_FiniteLivedIntangibleAssetsNetExcludingCustomerLists_6887330c-cabf-4500-87eb-2b8fe533f75d" xlink:href="bios-20250630.xsd#bios_FiniteLivedIntangibleAssetsNetExcludingCustomerLists"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsNoncurrent_0947e487-3474-40a1-b8da-bfba6c9733a0" xlink:to="loc_bios_FiniteLivedIntangibleAssetsNetExcludingCustomerLists_6887330c-cabf-4500-87eb-2b8fe533f75d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_c1f0e8af-5100-4901-80a8-d293f5e753cb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsNoncurrent_0947e487-3474-40a1-b8da-bfba6c9733a0" xlink:to="loc_us-gaap_Goodwill_c1f0e8af-5100-4901-80a8-d293f5e753cb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_6781d4e4-28f3-4b2b-9e98-9d5d6c66039c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsNoncurrent_0947e487-3474-40a1-b8da-bfba6c9733a0" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_6781d4e4-28f3-4b2b-9e98-9d5d6c66039c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_5d83d3cd-5725-4387-bcab-a74dd0e84d47" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsNoncurrent_0947e487-3474-40a1-b8da-bfba6c9733a0" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_5d83d3cd-5725-4387-bcab-a74dd0e84d47" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_bios_FiniteLivedCustomerListsNet_441f57c3-121a-4721-9710-1864e8b6eb65" xlink:href="bios-20250630.xsd#bios_FiniteLivedCustomerListsNet"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsNoncurrent_0947e487-3474-40a1-b8da-bfba6c9733a0" xlink:to="loc_bios_FiniteLivedCustomerListsNet_441f57c3-121a-4721-9710-1864e8b6eb65" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_bd44ef29-07ae-4f01-bb3e-fade21af5960" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Liabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_5cc0c1de-4428-422e-a1f0-0873210d79f0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_bd44ef29-07ae-4f01-bb3e-fade21af5960" xlink:to="loc_us-gaap_LiabilitiesCurrent_5cc0c1de-4428-422e-a1f0-0873210d79f0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesNoncurrent_990c6d1b-3cc3-4c5f-b5eb-aae39ae2fefc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_bd44ef29-07ae-4f01-bb3e-fade21af5960" xlink:to="loc_us-gaap_LiabilitiesNoncurrent_990c6d1b-3cc3-4c5f-b5eb-aae39ae2fefc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesNoncurrent_e8ba8fc0-b9c4-42c6-a41f-24bd7e5f6a33" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesNoncurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_52ad9ff7-09df-427b-969a-94ce00a9e551" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_e8ba8fc0-b9c4-42c6-a41f-24bd7e5f6a33" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_52ad9ff7-09df-427b-969a-94ce00a9e551" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_a1b54b54-e736-43a6-9e80-54a0834a78e6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_e8ba8fc0-b9c4-42c6-a41f-24bd7e5f6a33" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_a1b54b54-e736-43a6-9e80-54a0834a78e6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_8323379b-91db-45c2-af6e-52f59eba6b7d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_e8ba8fc0-b9c4-42c6-a41f-24bd7e5f6a33" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_8323379b-91db-45c2-af6e-52f59eba6b7d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_5825f5b1-999b-4894-b500-a60451b4d6a1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredIncomeTaxLiabilitiesNet"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_e8ba8fc0-b9c4-42c6-a41f-24bd7e5f6a33" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_5825f5b1-999b-4894-b500-a60451b4d6a1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_53b87952-4edf-4dfd-81c1-293196dfe051" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_bios_AccruedExpensesAndOtherCurrentLiabilities_81d5ce8a-859c-43e4-ac29-718097b20ec8" xlink:href="bios-20250630.xsd#bios_AccruedExpensesAndOtherCurrentLiabilities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_53b87952-4edf-4dfd-81c1-293196dfe051" xlink:to="loc_bios_AccruedExpensesAndOtherCurrentLiabilities_81d5ce8a-859c-43e4-ac29-718097b20ec8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_71e3eabd-5f0a-46b6-8047-21c0a605ec14" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_53b87952-4edf-4dfd-81c1-293196dfe051" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_71e3eabd-5f0a-46b6-8047-21c0a605ec14" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_e0e9b796-7c36-4bf9-aee9-59a78fb8f5ec" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_53b87952-4edf-4dfd-81c1-293196dfe051" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_e0e9b796-7c36-4bf9-aee9-59a78fb8f5ec" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_3e0d103f-272d-40a7-ba02-2588fb67b274" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_53b87952-4edf-4dfd-81c1-293196dfe051" xlink:to="loc_us-gaap_LongTermDebtCurrent_3e0d103f-272d-40a7-ba02-2588fb67b274" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_b2126353-b001-4884-bc23-e633f1df7f9c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_53b87952-4edf-4dfd-81c1-293196dfe051" xlink:to="loc_us-gaap_AccountsPayableCurrent_b2126353-b001-4884-bc23-e633f1df7f9c" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.bioscrip.com/role/UNAUDITEDCONDENSEDCONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOME" xlink:type="simple" xlink:href="bios-20250630.xsd#UNAUDITEDCONDENSEDCONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOME"/>
  <link:calculationLink xlink:role="http://www.bioscrip.com/role/UNAUDITEDCONDENSEDCONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOME" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_f30223ce-3127-4a54-942c-9cfaaa96ed06" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestIncomeExpenseNonoperatingNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpense_edc2e3e7-8139-4506-afa1-c3505bb7b15d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestExpense"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_f30223ce-3127-4a54-942c-9cfaaa96ed06" xlink:to="loc_us-gaap_InterestExpense_edc2e3e7-8139-4506-afa1-c3505bb7b15d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentIncomeNet_4334b194-ea93-4662-8a08-e7ec01798f56" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InvestmentIncomeNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_f30223ce-3127-4a54-942c-9cfaaa96ed06" xlink:to="loc_us-gaap_InvestmentIncomeNet_4334b194-ea93-4662-8a08-e7ec01798f56" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_a2acbae1-2ca4-4245-be2e-edb0367a2ea1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_f30223ce-3127-4a54-942c-9cfaaa96ed06" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_a2acbae1-2ca4-4245-be2e-edb0367a2ea1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_10522ffd-d233-4785-8afd-bbfd86077527" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_69044c87-5f68-4ead-8a7e-ce818a0250c5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_10522ffd-d233-4785-8afd-bbfd86077527" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_69044c87-5f68-4ead-8a7e-ce818a0250c5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_53caaae9-e3b5-468f-91ab-2764cbb53748" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_31cfb25c-88c0-4437-9303-eceb62c86a92" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_53caaae9-e3b5-468f-91ab-2764cbb53748" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_31cfb25c-88c0-4437-9303-eceb62c86a92" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_ca3f9291-2c80-437c-9185-b3c9980f9271" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_53caaae9-e3b5-468f-91ab-2764cbb53748" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_ca3f9291-2c80-437c-9185-b3c9980f9271" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_4c5c6e4f-3203-4a63-a34e-9eaff9241688" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_1ff6a40a-6dcc-4930-9b21-eca08bcbc431" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_4c5c6e4f-3203-4a63-a34e-9eaff9241688" xlink:to="loc_us-gaap_NetIncomeLoss_1ff6a40a-6dcc-4930-9b21-eca08bcbc431" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_26b3fd8b-422b-4c90-a192-d2ad29e9d48d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_4c5c6e4f-3203-4a63-a34e-9eaff9241688" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_26b3fd8b-422b-4c90-a192-d2ad29e9d48d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_554cea40-f4e7-493f-ade7-e9e138f5bca5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GrossProfit"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_5c987e68-45d4-4100-80f7-f1f6b6c653c7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_GrossProfit_554cea40-f4e7-493f-ade7-e9e138f5bca5" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_5c987e68-45d4-4100-80f7-f1f6b6c653c7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_0e0c33f9-40e6-43c4-bab3-123bd82f929f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_GrossProfit_554cea40-f4e7-493f-ade7-e9e138f5bca5" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_0e0c33f9-40e6-43c4-bab3-123bd82f929f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_8844c252-4542-414b-a5c3-bcee5d43fe7e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_9bb2dbee-3813-4351-a31b-424764cbcee0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_8844c252-4542-414b-a5c3-bcee5d43fe7e" xlink:to="loc_us-gaap_OperatingIncomeLoss_9bb2dbee-3813-4351-a31b-424764cbcee0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_2cd71353-03fc-4d5c-9ee6-cb532c77d9b7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestIncomeExpenseNonoperatingNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_8844c252-4542-414b-a5c3-bcee5d43fe7e" xlink:to="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_2cd71353-03fc-4d5c-9ee6-cb532c77d9b7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_a713d88c-1f8b-459d-a9be-d5d8a8f27685" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingExpenses"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_5eb39fdf-0fea-4bd9-a4e7-afd8afbd8453" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_a713d88c-1f8b-459d-a9be-d5d8a8f27685" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_5eb39fdf-0fea-4bd9-a4e7-afd8afbd8453" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_650fb16e-f199-4ba4-8c9c-07c0abd4d556" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_a713d88c-1f8b-459d-a9be-d5d8a8f27685" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_650fb16e-f199-4ba4-8c9c-07c0abd4d556" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_1ffdc262-fe19-4a25-96b5-ece52fe8969d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_ced18c09-695f-495c-97eb-1ac90f80ecad" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GrossProfit"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_1ffdc262-fe19-4a25-96b5-ece52fe8969d" xlink:to="loc_us-gaap_GrossProfit_ced18c09-695f-495c-97eb-1ac90f80ecad" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_e23e3883-ce66-4196-b70c-71576b2f83a2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingExpenses"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_1ffdc262-fe19-4a25-96b5-ece52fe8969d" xlink:to="loc_us-gaap_OperatingExpenses_e23e3883-ce66-4196-b70c-71576b2f83a2" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.bioscrip.com/role/UNAUDITEDCONDENSEDCONSOLIDATEDSTATEMENTSOFCASHFLOWS" xlink:type="simple" xlink:href="bios-20250630.xsd#UNAUDITEDCONDENSEDCONSOLIDATEDSTATEMENTSOFCASHFLOWS"/>
  <link:calculationLink xlink:role="http://www.bioscrip.com/role/UNAUDITEDCONDENSEDCONSOLIDATEDSTATEMENTSOFCASHFLOWS" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_009d0f91-78ae-4f0d-b556-a825bf59e02e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f975d52a-7944-4f81-9aaf-5b8cdafa3ab8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_009d0f91-78ae-4f0d-b556-a825bf59e02e" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_f975d52a-7944-4f81-9aaf-5b8cdafa3ab8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_5ea28078-e457-4be7-9a24-2e41961c1f06" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_009d0f91-78ae-4f0d-b556-a825bf59e02e" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_5ea28078-e457-4be7-9a24-2e41961c1f06" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_1d31ded3-535d-4cae-abd6-ea9865160c26" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_009d0f91-78ae-4f0d-b556-a825bf59e02e" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_1d31ded3-535d-4cae-abd6-ea9865160c26" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInReceivables_1ce18b32-56b2-4709-9965-1031d7d729b2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInReceivables"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_IncreaseDecreaseInReceivables_1ce18b32-56b2-4709-9965-1031d7d729b2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_d4962a23-e975-44ae-b7fc-c7f831f5348d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_d4962a23-e975-44ae-b7fc-c7f831f5348d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentDividendsOrDistributions_7b776a60-36e5-460d-ae0e-7af30a2e868b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EquityMethodInvestmentDividendsOrDistributions"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_EquityMethodInvestmentDividendsOrDistributions_7b776a60-36e5-460d-ae0e-7af30a2e868b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_b6f7213e-0967-4167-b124-c317cec6b258" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInInventories"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_b6f7213e-0967-4167-b124-c317cec6b258" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_9838f0c1-1b12-4a66-83f2-1cb46af2db25" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromEquityMethodInvestments"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_9838f0c1-1b12-4a66-83f2-1cb46af2db25" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentAssetsAndLiabilitiesNet_ad99892e-1aba-4381-88ac-ac8bfb21f270" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInOtherNoncurrentAssetsAndLiabilitiesNet"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentAssetsAndLiabilitiesNet_ad99892e-1aba-4381-88ac-ac8bfb21f270" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeasePayments_8da4d589-f265-4ea9-a721-c7e38afd2a6e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeasePayments"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_OperatingLeasePayments_8da4d589-f265-4ea9-a721-c7e38afd2a6e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationAmortizationAndAccretionNet_f7d2dce1-a17a-4dae-ab65-fc56f9765a77" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DepreciationAmortizationAndAccretionNet"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_DepreciationAmortizationAndAccretionNet_f7d2dce1-a17a-4dae-ab65-fc56f9765a77" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities_10bbe423-0c59-48e4-ba88-826985b0fc54" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities_10bbe423-0c59-48e4-ba88-826985b0fc54" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_eb57b6a1-aebe-44de-bbf0-a3e0c7546559" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_eb57b6a1-aebe-44de-bbf0-a3e0c7546559" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherAccountsPayableAndAccruedLiabilities_b603b2d4-54a2-4be0-9ff7-0ce64761bd2a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInOtherAccountsPayableAndAccruedLiabilities"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherAccountsPayableAndAccruedLiabilities_b603b2d4-54a2-4be0-9ff7-0ce64761bd2a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_83eb6cca-33b4-4f5e-b171-94f28afc2963" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="12" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_NetIncomeLoss_83eb6cca-33b4-4f5e-b171-94f28afc2963" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayableTrade_e794e050-2ac2-4a82-ac2a-0a141c9c83b8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccountsPayableTrade"/>
    <link:calculationArc order="13" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayableTrade_e794e050-2ac2-4a82-ac2a-0a141c9c83b8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense_f1b425bc-1f5a-4e9d-801f-673c05b2257e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense"/>
    <link:calculationArc order="14" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense_f1b425bc-1f5a-4e9d-801f-673c05b2257e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherOperatingActivitiesCashFlowStatement_63277808-c2e0-40fb-98ed-03507a4307bb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherOperatingActivitiesCashFlowStatement"/>
    <link:calculationArc order="15" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_OtherOperatingActivitiesCashFlowStatement_63277808-c2e0-40fb-98ed-03507a4307bb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_2ce4eaac-30da-4e29-8815-271f6234724d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts"/>
    <link:calculationArc order="16" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_2ce4eaac-30da-4e29-8815-271f6234724d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_5741f90f-9612-4753-9549-d646ddadcd39" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensation"/>
    <link:calculationArc order="17" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_ShareBasedCompensation_5741f90f-9612-4753-9549-d646ddadcd39" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_6d5630bb-0f71-4a8b-a9cf-eb5a6d21fcf0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:calculationArc order="18" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0f1b4a24-9496-41ed-8b03-ddbeee5bc5be" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_6d5630bb-0f71-4a8b-a9cf-eb5a6d21fcf0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_bc717499-9ca6-43ff-b16d-16a85f0b99bd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_b933519e-69dd-4693-a607-84cabab562cf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_bc717499-9ca6-43ff-b16d-16a85f0b99bd" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_b933519e-69dd-4693-a607-84cabab562cf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_f1a077ac-6826-421a-9898-48d45fa80b00" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_bc717499-9ca6-43ff-b16d-16a85f0b99bd" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_f1a077ac-6826-421a-9898-48d45fa80b00" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_31f9823e-a5cb-4c9f-87a4-3d3ad23491bb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_345ee534-bdad-4e1a-be8f-66f0ced29f3f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromPaymentsForOtherFinancingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_31f9823e-a5cb-4c9f-87a4-3d3ad23491bb" xlink:to="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_345ee534-bdad-4e1a-be8f-66f0ced29f3f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_bf0b535f-6d21-41ed-b1fd-6e5616d646db" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_31f9823e-a5cb-4c9f-87a4-3d3ad23491bb" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_bf0b535f-6d21-41ed-b1fd-6e5616d646db" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfDebt_b1fa8ca9-a641-4a4f-af7e-7ff5cb3d3400" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfDebt"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_31f9823e-a5cb-4c9f-87a4-3d3ad23491bb" xlink:to="loc_us-gaap_RepaymentsOfDebt_b1fa8ca9-a641-4a4f-af7e-7ff5cb3d3400" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_b16b2c31-10e2-4e61-9f30-7278fca9b47b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_31f9823e-a5cb-4c9f-87a4-3d3ad23491bb" xlink:to="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_b16b2c31-10e2-4e61-9f30-7278fca9b47b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfDebt_5ed6a219-8dd6-4bd6-ac2a-2190f45d66be" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromIssuanceOfDebt"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_31f9823e-a5cb-4c9f-87a4-3d3ad23491bb" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfDebt_5ed6a219-8dd6-4bd6-ac2a-2190f45d66be" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDebtIssuanceCosts_ab3d1cba-c6c8-413e-be36-33a8734a99cc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsOfDebtIssuanceCosts"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_31f9823e-a5cb-4c9f-87a4-3d3ad23491bb" xlink:to="loc_us-gaap_PaymentsOfDebtIssuanceCosts_ab3d1cba-c6c8-413e-be36-33a8734a99cc" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.bioscrip.com/role/BUSINESSCOMBINATIONSPreliminaryEstimateoftheAllocationConsiderationTransferredDetails" xlink:type="simple" xlink:href="bios-20250630.xsd#BUSINESSCOMBINATIONSPreliminaryEstimateoftheAllocationConsiderationTransferredDetails"/>
  <link:calculationLink xlink:role="http://www.bioscrip.com/role/BUSINESSCOMBINATIONSPreliminaryEstimateoftheAllocationConsiderationTransferredDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_56df6e1f-ef04-4de0-b665-319c56cec5c8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAcquiredFromAcquisition_fa97d863-db5d-438e-8885-2ebd7b1659f2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAcquiredFromAcquisition"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_56df6e1f-ef04-4de0-b665-319c56cec5c8" xlink:to="loc_us-gaap_CashAcquiredFromAcquisition_fa97d863-db5d-438e-8885-2ebd7b1659f2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferred1_4882e109-7f60-4341-89f9-e3248751fa02" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationConsiderationTransferred1"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_56df6e1f-ef04-4de0-b665-319c56cec5c8" xlink:to="loc_us-gaap_BusinessCombinationConsiderationTransferred1_4882e109-7f60-4341-89f9-e3248751fa02" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_8d2e2da6-b015-4c02-ae2a-8ffcfadf61aa" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables_fce7cdf9-bf94-4b7d-b049-15a1c5066260" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_8d2e2da6-b015-4c02-ae2a-8ffcfadf61aa" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables_fce7cdf9-bf94-4b7d-b049-15a1c5066260" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles_8d0dfb65-f950-4b3a-b962-0e6195af69a9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_8d2e2da6-b015-4c02-ae2a-8ffcfadf61aa" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles_8d0dfb65-f950-4b3a-b962-0e6195af69a9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedInventory_6b75bb35-3c61-4563-9cda-25cbf1bf7e3f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedInventory"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_8d2e2da6-b015-4c02-ae2a-8ffcfadf61aa" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedInventory_6b75bb35-3c61-4563-9cda-25cbf1bf7e3f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherNoncurrentAssets_89a9d12f-3e68-451d-bf2c-0a2e06c9b9c5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherNoncurrentAssets"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_8d2e2da6-b015-4c02-ae2a-8ffcfadf61aa" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherNoncurrentAssets_89a9d12f-3e68-451d-bf2c-0a2e06c9b9c5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_bios_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAccountsPayableAndOtherLiabilities_f2c0c354-6f22-4155-9600-edec416d1ac0" xlink:href="bios-20250630.xsd#bios_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAccountsPayableAndOtherLiabilities"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_8d2e2da6-b015-4c02-ae2a-8ffcfadf61aa" xlink:to="loc_bios_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAccountsPayableAndOtherLiabilities_f2c0c354-6f22-4155-9600-edec416d1ac0" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.bioscrip.com/role/EARNINGSPERSHAREScheduleofBasicandDilutedEarningsLossDetails" xlink:type="simple" xlink:href="bios-20250630.xsd#EARNINGSPERSHAREScheduleofBasicandDilutedEarningsLossDetails"/>
  <link:calculationLink xlink:role="http://www.bioscrip.com/role/EARNINGSPERSHAREScheduleofBasicandDilutedEarningsLossDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_66ec67d4-1ab2-4f91-ac67-3b2c85892ffa" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_08846569-a600-4d1d-877a-9fdfff75e9f2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_66ec67d4-1ab2-4f91-ac67-3b2c85892ffa" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_08846569-a600-4d1d-877a-9fdfff75e9f2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_a8d39379-316d-4047-ba5f-13935921ab4d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_66ec67d4-1ab2-4f91-ac67-3b2c85892ffa" xlink:to="loc_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_a8d39379-316d-4047-ba5f-13935921ab4d" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.bioscrip.com/role/LEASESScheduleofOperatingLeasesMatureDetails" xlink:type="simple" xlink:href="bios-20250630.xsd#LEASESScheduleofOperatingLeasesMatureDetails"/>
  <link:calculationLink xlink:role="http://www.bioscrip.com/role/LEASESScheduleofOperatingLeasesMatureDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_11a86d78-6b58-4132-abb5-0bac21dd6588" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_b1842028-2cfe-4db9-98fe-04c0e4ae4686" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_11a86d78-6b58-4132-abb5-0bac21dd6588" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_b1842028-2cfe-4db9-98fe-04c0e4ae4686" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_2b1f042e-7e85-4ffd-b191-aea15613591d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_11a86d78-6b58-4132-abb5-0bac21dd6588" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_2b1f042e-7e85-4ffd-b191-aea15613591d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_cc39ad1c-e17f-4adc-aa5a-8b5a5df1ca2e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_11a86d78-6b58-4132-abb5-0bac21dd6588" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_cc39ad1c-e17f-4adc-aa5a-8b5a5df1ca2e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_9dd052f3-1ba3-4be6-a39e-ad787c9fc59c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_11a86d78-6b58-4132-abb5-0bac21dd6588" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_9dd052f3-1ba3-4be6-a39e-ad787c9fc59c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_a7ba4ca1-19dd-4839-9a46-7c477abca1e5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_11a86d78-6b58-4132-abb5-0bac21dd6588" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_a7ba4ca1-19dd-4839-9a46-7c477abca1e5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_bios_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour_fa614817-ff83-4c0b-8104-f124f5f31d9a" xlink:href="bios-20250630.xsd#bios_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_11a86d78-6b58-4132-abb5-0bac21dd6588" xlink:to="loc_bios_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour_fa614817-ff83-4c0b-8104-f124f5f31d9a" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.bioscrip.com/role/LEASESScheduleofOperatingLeasesMatureDetails_1" xlink:type="simple" xlink:href="bios-20250630.xsd#LEASESScheduleofOperatingLeasesMatureDetails_1"/>
  <link:calculationLink xlink:role="http://www.bioscrip.com/role/LEASESScheduleofOperatingLeasesMatureDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_a67f4d74-e510-4258-bcf4-5fd6040f7990" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_43958ad4-46b5-4f18-8ae7-9854cc0133a2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_a67f4d74-e510-4258-bcf4-5fd6040f7990" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_43958ad4-46b5-4f18-8ae7-9854cc0133a2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_886631b6-9aae-430f-b394-0e8a172e2d7d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_a67f4d74-e510-4258-bcf4-5fd6040f7990" xlink:to="loc_us-gaap_OperatingLeaseLiability_886631b6-9aae-430f-b394-0e8a172e2d7d" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.bioscrip.com/role/PROPERTYANDEQUIPMENTDetails" xlink:type="simple" xlink:href="bios-20250630.xsd#PROPERTYANDEQUIPMENTDetails"/>
  <link:calculationLink xlink:role="http://www.bioscrip.com/role/PROPERTYANDEQUIPMENTDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_9bcf7131-58ef-423e-a70d-acb3c18f6799" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_ef239b75-9597-4dec-a471-c6018cce6325" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_9bcf7131-58ef-423e-a70d-acb3c18f6799" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_ef239b75-9597-4dec-a471-c6018cce6325" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_f3b4a371-12d1-4111-a9ec-9846f9f86d1e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_9bcf7131-58ef-423e-a70d-acb3c18f6799" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_f3b4a371-12d1-4111-a9ec-9846f9f86d1e" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.bioscrip.com/role/GOODWILLANDOTHERINTANGIBLEASSETSCarryingAmountandAccumulatedAmortizationofIntangibleAssetsDetails" xlink:type="simple" xlink:href="bios-20250630.xsd#GOODWILLANDOTHERINTANGIBLEASSETSCarryingAmountandAccumulatedAmortizationofIntangibleAssetsDetails"/>
  <link:calculationLink xlink:role="http://www.bioscrip.com/role/GOODWILLANDOTHERINTANGIBLEASSETSCarryingAmountandAccumulatedAmortizationofIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_465dfa1b-638d-48ca-a16e-143cab7310ef" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_03a1a5e6-e1a7-486c-aef9-fd4498d0762e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_465dfa1b-638d-48ca-a16e-143cab7310ef" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_03a1a5e6-e1a7-486c-aef9-fd4498d0762e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_456cbe9e-49b2-4e9d-b6ef-334341eb9d95" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_465dfa1b-638d-48ca-a16e-143cab7310ef" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_456cbe9e-49b2-4e9d-b6ef-334341eb9d95" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.bioscrip.com/role/INDEBTEDNESSScheduleofDebtDetails" xlink:type="simple" xlink:href="bios-20250630.xsd#INDEBTEDNESSScheduleofDebtDetails"/>
  <link:calculationLink xlink:role="http://www.bioscrip.com/role/INDEBTEDNESSScheduleofDebtDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_a59efbd0-d511-46bd-8d00-192cf5f5aee1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebt"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_cf57c514-8957-4011-b577-95f0a2a5e66b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_a59efbd0-d511-46bd-8d00-192cf5f5aee1" xlink:to="loc_us-gaap_LongTermDebtCurrent_cf57c514-8957-4011-b577-95f0a2a5e66b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_d4a36e2f-d05a-4bed-89b7-e08083ae50bc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_a59efbd0-d511-46bd-8d00-192cf5f5aee1" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_d4a36e2f-d05a-4bed-89b7-e08083ae50bc" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.bioscrip.com/role/INDEBTEDNESSScheduleofDebtDetails_1" xlink:type="simple" xlink:href="bios-20250630.xsd#INDEBTEDNESSScheduleofDebtDetails_1"/>
  <link:calculationLink xlink:role="http://www.bioscrip.com/role/INDEBTEDNESSScheduleofDebtDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_f1d297b4-86fe-4332-b76f-96f9ff43f66e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebt"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_b9e9429d-c58c-4ece-9a43-85c12497fe77" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_f1d297b4-86fe-4332-b76f-96f9ff43f66e" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_b9e9429d-c58c-4ece-9a43-85c12497fe77" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscount_de3d1156-7a55-4c26-a835-e80e0166e155" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentUnamortizedDiscount"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_f1d297b4-86fe-4332-b76f-96f9ff43f66e" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscount_de3d1156-7a55-4c26-a835-e80e0166e155" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFinanceCostsNet_e64c4780-53ef-494d-8850-392fb5409789" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredFinanceCostsNet"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_f1d297b4-86fe-4332-b76f-96f9ff43f66e" xlink:to="loc_us-gaap_DeferredFinanceCostsNet_e64c4780-53ef-494d-8850-392fb5409789" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.bioscrip.com/role/INDEBTEDNESSScheduleofLongTermDebtMaturitiesDetails" xlink:type="simple" xlink:href="bios-20250630.xsd#INDEBTEDNESSScheduleofLongTermDebtMaturitiesDetails"/>
  <link:calculationLink xlink:role="http://www.bioscrip.com/role/INDEBTEDNESSScheduleofLongTermDebtMaturitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_bd5d32c9-e9fa-4bc4-adce-f70e27dfff7c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear_22a87ddd-a250-4f7d-8d2b-9c22a5e0cb8b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_bd5d32c9-e9fa-4bc4-adce-f70e27dfff7c" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear_22a87ddd-a250-4f7d-8d2b-9c22a5e0cb8b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_f6714561-de0f-4739-b82e-d4ab2186f149" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_bd5d32c9-e9fa-4bc4-adce-f70e27dfff7c" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_f6714561-de0f-4739-b82e-d4ab2186f149" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_a9fd54c2-1846-4808-8117-1013f3ea5bb3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_bd5d32c9-e9fa-4bc4-adce-f70e27dfff7c" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_a9fd54c2-1846-4808-8117-1013f3ea5bb3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_eb3c752b-3fbd-4d60-a5c2-ea3298f1ac9b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_bd5d32c9-e9fa-4bc4-adce-f70e27dfff7c" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_eb3c752b-3fbd-4d60-a5c2-ea3298f1ac9b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_0b949ce5-393d-428f-880a-4c59cd648f88" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_bd5d32c9-e9fa-4bc4-adce-f70e27dfff7c" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_0b949ce5-393d-428f-880a-4c59cd648f88" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.bioscrip.com/role/SEGMENTREPORTINGDetails" xlink:type="simple" xlink:href="bios-20250630.xsd#SEGMENTREPORTINGDetails"/>
  <link:calculationLink xlink:role="http://www.bioscrip.com/role/SEGMENTREPORTINGDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_d9cddb54-ce87-408a-b5b4-f9522bdb2415" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Revenues_adc88c54-c14d-4840-bf9f-97b95ca8f94f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Revenues"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_d9cddb54-ce87-408a-b5b4-f9522bdb2415" xlink:to="loc_us-gaap_Revenues_adc88c54-c14d-4840-bf9f-97b95ca8f94f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfRevenue_0c874327-d59e-41d2-821e-3ec5827bec71" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CostOfRevenue"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_d9cddb54-ce87-408a-b5b4-f9522bdb2415" xlink:to="loc_us-gaap_CostOfRevenue_0c874327-d59e-41d2-821e-3ec5827bec71" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LaborAndRelatedExpense_ee199425-dd5b-47cc-8be3-2eb5d2ad08b9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LaborAndRelatedExpense"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_d9cddb54-ce87-408a-b5b4-f9522bdb2415" xlink:to="loc_us-gaap_LaborAndRelatedExpense_ee199425-dd5b-47cc-8be3-2eb5d2ad08b9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCostAndExpenseOperating_323958ac-dda1-4c55-b1f1-d65a20928ba3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherCostAndExpenseOperating"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_d9cddb54-ce87-408a-b5b4-f9522bdb2415" xlink:to="loc_us-gaap_OtherCostAndExpenseOperating_323958ac-dda1-4c55-b1f1-d65a20928ba3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_40220fb6-6ecf-4db5-b6a0-3e37b8bd3ddb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_d9cddb54-ce87-408a-b5b4-f9522bdb2415" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_40220fb6-6ecf-4db5-b6a0-3e37b8bd3ddb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseNonoperating_e914abc2-0b77-4436-9d28-4a747ddf6032" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestExpenseNonoperating"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_d9cddb54-ce87-408a-b5b4-f9522bdb2415" xlink:to="loc_us-gaap_InterestExpenseNonoperating_e914abc2-0b77-4436-9d28-4a747ddf6032" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_e990aa6c-2a28-4f88-b419-8ccd7db74b64" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromEquityMethodInvestments"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_d9cddb54-ce87-408a-b5b4-f9522bdb2415" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_e990aa6c-2a28-4f88-b419-8ccd7db74b64" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_ef76a7f7-4fe8-43f4-bc3a-b8cc5dd15bda" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_d9cddb54-ce87-408a-b5b4-f9522bdb2415" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_ef76a7f7-4fe8-43f4-bc3a-b8cc5dd15bda" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_df7fffc9-7dec-4127-ac59-154ac8216052" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:calculationArc order="9" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_d9cddb54-ce87-408a-b5b4-f9522bdb2415" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_df7fffc9-7dec-4127-ac59-154ac8216052" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Revenues_1383f5b7-e232-4fcb-a5a3-818c6026cab9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Revenues"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_29d16b67-85a9-4631-b0b7-0fcec099a443" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Revenues_1383f5b7-e232-4fcb-a5a3-818c6026cab9" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_29d16b67-85a9-4631-b0b7-0fcec099a443" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherIncome_685a7979-95f3-45e8-83d3-5f6a6866a927" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherIncome"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Revenues_1383f5b7-e232-4fcb-a5a3-818c6026cab9" xlink:to="loc_us-gaap_OtherIncome_685a7979-95f3-45e8-83d3-5f6a6866a927" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
